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with Notch-ICD displays a synergistic effect between Importin-a3 and Notch activation on cell proliferation in the eye and wing imaginal discs which is likely to be caused by stronger activation of Notch signals due to the greater import of Notch-ICD into the nucleus by overexpressed Importin-a3. Our results establish that the nuclear transport of Notch-ICD is mediated by the canonical Importin-a3
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