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Ytes. Conclusions: These results demonstrate that in RBA-1 cells, activation of c-Jun/AP-1 by a CaMKII-dependent PI3K/ Akt-JNK activation mediated through transactivation of PDGFR is essential for up-regulation of MMP-9 and cell migration induced by LTA. Understanding the regulatory mechanisms underlying LTA-induced MMP-9 expression and functional changes in astrocytes may provide a new therapeuti
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Al lung tissues and five of seven NSCLC tissues. Consequently, asAl lung tissues and five of seven NSCLC tissues. As a result, as with the Ex4a(+)WT1 isoform in standard cells, in a few of 7 paired samples, usual lung tissues expressed the Ex4a(+)WT1 isoform at concentrations similar to these in lung most cancers tissues. Apparently, during the remaining four paired samples, normal lung tiss
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