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Nautoimmune hyperthyroidism as a result of TSH receptor gene mutation (TSHR) (until now 55 various mutations and over a dozen cases of de novo germinal mutations have been described);6. hyperthyroidism associated with McCune-Albright syndrome (in about 30 of patients with this syndrome; McCune-Albright syndrome frequency of occurrence is estimated - 1:10 000-1:1 000 000; background - mutation in

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